According to Iraq's Saberin News, the attack took place in the vicinity of the city of Nasiriyah on Tuesday.
No group has claimed responsibility for the blast yet.
Anti-US sentiments have been running high in Iraq since Washington assassinated top Iranian commander Ghasem Soleimani and the second-in-command of the Iraqi popular mobilization units, Abu Mahdi al-Muhandis, in January last year.
Following the attack, Iraqi lawmakers unanimously approved a bill on January 5, demanding the withdrawal of all foreign troops.
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