The new announcement of the Asian Football Confederation comes nearly one year after the qualifiers were postponed by the body due to the COVID-19 outbreak.
Dragan Skocic's team will take on Hong Kong on March 25, 2021, before facing Cambodia five days later.
Persian leopards will then lock horns with Bahrain on June 7 and Iraq on June 15.
Iran sits third in the Group C of the qualifiers with six points while Iraq and Bahrain lead the table with 11 and 9 points respectively.
Team Melli needs to win the four remaining matches for a confident berth to the next round but it may also win the quota by winning nine more points.
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