Mashhad-Yazd train was carrying 348 passengers, Mohammadreza Daghayeghi said, adding three wagons of the train went off track.
Some 5 passengers are in critical conditions, he said, adding that they have been dispatched to the hospital.
He went on to say that nine rescue teams of the IRCS are carrying out the necessary relief measures.
Two helicopters have been dispatched to the location, he said, noting that air and ground relief is being carried out to transport the injured of the incident.
The derailment incident took place near Mazino Station at 5:30 a.m (local time) on June 8, 2022.
Passing an excavator over the track has been announced as the cause of the incident.
AMK/5509043