The Palestinian media reported on Friday that most of the victims of the Israeli assault were women and children.
The death toll is likely to rise due to the number of seriously wounded people.
The attack hit a residential home in Tal as-Sultan neighborhood in Rafah.
It comes as the Israeli military is preparing evacuation plans for the city in anticipation of a ground offensive.
The United Nations and many other countries have expressed grave concern over the offensive.
The city is home to approximately 1.5 million displaced Palestinians.
The regime began the war on October 7 after Gaza’s Resistance groups carried out a retaliatory operation against the usurping entity. Since the start of the offensive, the Tel Aviv regime has killed more than 34,000 Palestinians, most of them women and children.
AMK/PressTV