Foreign Ministry spokesman Nasser Kan'ani made the remarks in a post on X on Friday.
Earlier, the International Court of Justice (ICJ) issued an interim ruling in a case lodged against the regime by South Africa, ordering Tel Aviv to take all measures within its power to prevent genocide in Gaza.
Israeli officials reacted by accusing the ICJ of "antisemitic" bias.
"The Zionist regime's hostile reaction [to the ruling] showed that the regime's foundation is based upon aggression and discrimination, and [that] it lends no credence to the international legal norms and regulations," Kan'ani wrote.
The Israeli regime has been waging war against Gaza since October 7, 2023, following an operation carried out by the Palestinian territory's Resistance groups.
More than 26,000 Palestinians, some 70 percent of whom are women, children, and adolescents, have been killed in the brutal onslaught so far, while upwards of 64,100 others have been injured.
Kan'ani also commented on a response issued to the ruling by the United States, which has said it believed the genocide allegations were "unfounded."
"The type of attitude [adopted] by the US administration [towards the ruling], indicates Washington's instrumentalization of international judicial mechanisms," Kan'ani added.
The spokesman said, "Although belatedly," the ICJ ruling "serves as a testament to the bitter reality that what is going on in Gaza is an instance of international crimes, including genocide, which is and continues to be committed with the US administration's unlimited support for the Zionist regime."
The US has been providing the war with all-out military and political support. It has armed the regime with more than 10,000 tons of military hardware, and blocked ratification of all United Nations Security Council resolutions that have called for cessation of the Israeli aggression.
The spokesman concluded his remarks by saying, "The people of the world are now faced with the question that what additional permission do the international organizations and institutions [tasked with] preserving the international peace and security need to force the Zionist regime into stopping the genocide?"
MP/PressTV