Captopril is an edible drug that plays an essential role in the treatment of heart attack, heart malfunction and high blood pressure and persistent consumption of this drug results in side effects.
According to Iran Nanotechnology Council (INIC), Iranian researchers presented an accurate and simple method to measure this drug with high sensitivity. Sensors produced in this method are cheaper than the similar samples while they have higher sensitivity. In addition, the production of these sensors does not pollute the environment.
According to the researchers, the aim of the study was to design and produce an electrode made of gold with nanoporous structure, which is doped with two noble metals of ruthenium and palladium. The simultaneous effect of these metals increases the catalytic activity, which consequently results in the better performance of the sensor to detect and measure captopril.
The implementation of sensors produced in this research resulted in appropriate and desirable results in the measurement of captopril in real samples, including human blood serum and tablet. In fact, measurement of the drug is carried out with higher speed and accuracy but less cost by using the produced sensors in comparison with the similar methods.
The production of sensor through the method presented in this research not only requires fewer amounts of ruthenium and palladium expensive metals, but also significantly increases the sensitivity to detect and measure captopril. In addition, this method is biocompatible because no toxic material is used in the production of the sensors.
Results of the research have been published in Electrochimica Acta, vol. 164, 2015, pp. 1-11.
MS/PR