Flash floods and landslides have occurred in six regions in the province since Thursday evening.
Parts of the provincial highway were reportedly inundated, causing huge traffic jams, according to Xinhua.
The head of the South Sulawesi disaster mitigation agency Amson Pandolo told local media that those killed were identified as villagers of Latimojong in the region of Luwu.
The number of houses and public facilities damaged in the disasters remained unknown, and rescuers have focused their efforts on evacuating and helping the affected people, he added.
MP/PR