Magnetic nanoparticles to treat cancer

News ID: 2788557 -
TEHRAN, Jun. 27 (MNA) – Researchers at University of Tehran have made a breakthrough in the synthesis of magnetic nanoparticles which can be used as a good alternative in cancer treatment

One way to treat cancer and kill cancer cells is through injecting magnetic nanoparticles into the cancerous tissue. Once the magnetic nanoparticles are exposed to the cancer cells and naturally some healthy cells as well, an alternating magnetic field outside the patient's body will raise the temperature of these nanoparticles and generate heat. The heat then targets and kills the cancer cells in a process that is called Hyperthermia therapy.

Researchers at University of Tehran have worked on a project in which ceramic nanoparticles of lanthanum magnetite doped with strontium (La0.8Sr0.2MnO3) was produced through mechanical grinding and heating.

Dr. Abolghasem Ataei, the project manager, said the most important issue in such treatment is to properly set the temperature known as Curie temperature where the nanoparticles lose their magnetism and their temperature will not increase.

“Thus, by applying a magnetic field, no more heat is generated and since cancer cells are killed in a lower temperature than healthy cells, the temperature for nanoparticles must be higher than the temperature for killing cancer cells and lower than the point that would be damaging to healthy ones. We have succeeded in obtaining such temperature in this project,” he said.

The results of the research conducted by Dr. Abolghasem Ataei, Seyed Mohammad Salili, Dr. Mohammadreza Barati, and Zoya Seddighi have been issued in Materials Characterization (volume 106, issue no. 1, 2015, pp. 78-85).

 

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